Next-Generation Lipid Nanoparticles

Targeted Coacervates Enabled by Polyphenol-Peptide Networks for Therapeutic Delivery.

Linli Jiang, Qiantao Song, Zhixing Lin, Hai Liu, Jingqu Chen, Xiangchun Zhang, Hui Li, Christina Cortez-Jugo, Jiajing Zhou, Lei Liu, Frank Caruso, Hejin Jiang

2026-05-25

Precise intracellular delivery remains a critical barrier to the efficacy of therapeutic biomolecules. Coacervates, with their hig..

Sub-nm Pore Size Engineering in Metal–Phenolic Membranes

YZ Chen, QZ Zhong, JRT Chen, X Chen, Z Wang, JJ Richardson, Y Lv, T Liu, F Caruso

2026-03-25

Metal–organic membranes with tunable nanopores provide a versatile platform for energy-efficient, high-precision separations. Howe..

Polyphenol-Mediated Engineering of Lipid Nanoparticles With Crystalline Mesophases.

Shiyao Li, Patrick Charchar, Haitao Yu, Zhixing Lin, Hamish G Brown, Wanjun Xu, Chan-Jin Kim, Irene Yarovsky, Yi Ju, Frank Caruso

2025-09-15

Lipids self-assemble into lipid nanoparticles (LNPs) with different crystalline mesophases, including lamellar and nonlamellar (e...